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STUDY LOCATION 

ENTRY YEARS

NUMBER OF PARTICIPANTS (MILLIONS)

STORED BLOOD

AMERICAS

American Cancer Society Cancer Prevention Study I 1959 - 1960 1.0 (M&F) No
American Cancer Society Cancer Prevention Study II 1982 - 1983 1.2 (M&F) Yes
American Cancer Society Cancer Prevention Study III 2006 - 2013 0.3 (M & F) Yes
AllofUs (US Precision Medicine Initiative) 2018 - 0.22*  (M&F)  Yes
California Teachers Study (CTS) 1995 - 1996 0.13 (F) Yes
Cooper Center Longitudinal Study 1970 - 0.11*  (M&F) Yes
Connect For Cancer Prevention Study (Connect) 2021 - 2027 0.2* (M&F) Yes
Cuba Prospective Study 1996 - 2002 0.15 (M&F) No
Health Professionals' Follow Up Study (HPFS) 1986 0.05 (M) Yes
Kaiser Permanente Research Program on Genes, Environment, and Health (RPGEH) 2008 - 0.21*  (M&F) Yes
Mexico City Prospective Study 1998 - 2004 0.15 (M&F) Yes
Million Veteran Program 2011 - 0.75*  (M&F) Yes
Multi-ethnic Cohort Study 1993 -1997 0.2 (M&F) Yes
National Health Interview Survey 1997-2004 0.2 (M&F) No
Newfoundland and Labrador Genome Project 2018 - 0.52*  (M&F) Yes
NIH-AARP Diet and Health Study 1995 -1996 0.57 (M&F) No
Nurses' Health Study I  1976 - 1976 0.12 (F) Yes
Nurses' Health Study 2 1989 - 1989 0.12 (F) Yes
Nurses' Health Study 3 2010 - (M&F) Yes
Ontario Health Study (OHS) 2010 -2017 0.23 (M&F) Yes
Physicians' Health Study I & II (PHS) 1982 - 2011 0.04 (M) Yes
Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial (PLCO) 1993 - 2001 0.15 (M&F) Yes
Women's Health Initiative (WHI) 1993 -1998 0.09 (F) Yes
Women's Health Study 1992 - 1995 0.04 (F) Yes

ASIA

BangladEsh Longitudinal Investigation of Emerging Vascular Events study (BELIEVE) 2016 - 2020 0.08 (M&F) Yes
Chennai Prospective Study 1998 - 2001 0.5 (M&F) No
China Kadoorie Biobank 2004 - 2008 0.5 (M&F) Yes
Elderly Health Service, Hong Kong 1998 - 2001 0.13 (M&F) No

Indian Study of Healthy Ageing (ISHA)

0.2* Yes
Japan Public Health Center-based Prospective Study (JPHC Study) 1990 - 1993 0.14 (M&F) Yes
Japan Public Health Center-based Prospective Study for the Next generation (JPHC-NEXT) 2011 - 2016 0.12 (M&F) Yes
Kailuan study 2006 - 2007 0.1 (M&F) Yes
Kangbuk Samsung Health Study 2002 - 0.28*  (M&F) Yes
Korean Cancer Prevention Study I
1992 - 1995 1.32 (M&F) No
Korean Cancer Prevention Study II 2004 - 2011 0.15 (M&F)
Yes
Korean Genome and EpidemiologyStudy (KoGES) 2001 - 2013 0.25 (M&F) Yes
 Longitudinal Health Insurance Database 2000 1996 - 2000 0.20 (M&F) No
Malaysian Cohort 2007-2013 0.11 (M&F) Yes
Mumbai  Studies 1991 - 1997 0.15 (M&F) No
PERSIAN Cohort Study 2014 - 0.18*  (M&F) Yes
Qatar Genome Programme (& Biobank)
2015 - Yes
Russian Prospective Study 1999 - 2008 0.21 (M&F) Yes
Saudi Human Genome Program (SHGP)
2013 - 0.1*  (M&F) Yes
Shanghai Men's Health Study 2002 - 2006 0.06 (M) Yes
Shanghai Womens' Health Study 1997 - 2000 0.07 (F) Yes
Taiwan Biobank 2012 - 0.1*  (M&F) Yes
Taiwan MJ Cohort Study 1994 0.59 (M&F) Yes
Taizhou Biobank /Taizhou Longitudinal Cohort Study
2007- 0.2*  (M&F) Yes
Tohoku Medical Megabank Project 2013 - 2016 0.14 (M&F) Yes
Trivandrum Urban/Rural Tobacco Study 2002 - 2006 0.4 (M) Some

AUSTRALAsia

45 and Up 2006 - 2009 0.26 (M&F) Yes

EUROPE

Apolipoprotein-related Mortality RISk (AMORIS) 1985 - 1996 0.81 (M&F) Yes
Constances 2012 - 2019 0.21  (M&F) Yes
EPIC (European Prospective Investigation into Cancer and Nutrition) 1992 - 1999 0.52 (M&F) Yes
Generations Study (Breakthrough Generations) 2003 - 2015 0.11 (F) Yes
German National Cohort (NAKO) 2014- 0.1* (M&F) Yes
JANUS Serum Bank 1973 - 2004 0.32 (M&F) Yes
Lifelines Cohort Study & Biobank 2006 - 2013 0.17 (M&F) Yes
Million Women Study 1996 - 2001 1.32 (F) Yes
Netherlands Cohort Study 1986 - 1986 0.12 (M&F) No
Nord-Trondelag Health Study (HUNT) 1984 - 2019 0.17 (M&F) Yes
Norwegian Family Based Life Course Study 1960 - 2011 5.2 (M&F) Yes
Norwegian Women and Cancer study 1991 - 2006 0.17 (F) Yes
Stockholm Public Health Cohort (SPHC) 2002 - 2010 0.1 (M&F) No
UK Biobank 2006 - 2010 0.5 (M&F) Yes
UK Blood Donor Cohorts (INTERVAL & COMPARE) 2012 - 0.1*  (M&F) Yes
UKCTOCS (UK Collaborative Trial of Ovarian Cancer Screening) Longitudinal Women’s Cohort (UKLWC) 2001 - 2005 0.2 (F) Yes
Vorarlberg Health Monitoring  and Promotion Programme 1985 - 2005 0.19 (M&F) Yes

INTERNATIONAL

PURE (Prospective Urban Rural Epidemiological Study) 2003 - 2009 0.4 (M&F) Yes

collABORATIONS OF PROSPECTIVE STUDIES 

Asia Cohort Consortium (ACC) Various 1.1 (M&F)
Asia-Pacific Cohort Studies Collaboration 1981 - 1992 0.6 (M&F) Yes
BBMRI-NL Biobank Various 0.4 (M&F) Yes
Canadian Partnership for Tomorrow's Health  (CanPath) 2009 - 2016 0.33 (M&F) Yes
Cohort of Norway (CONOR) 1994 - 2003 0.19 (M&F) No
Emerging Risk Factors Collaboration Various 2.3 (M&F) No
Global BMI Mortality Collaboration Various 10.6 (M&F) No
Japanese Prospective Studies Various 0.4 (M&F) No
LIFEPATH (Life-course biological pathways underlying social differences in healthy aging) 0.24 (M&F) Yes
Northern Sweden Health and Disease Study 1985 - 0.14 (M&F) Yes
Prospective Studies Collaboration Various 1.2 (M&F) No
Taiwan Prospective Studies 1999 - 2009 0.5 (M&F) Yes
US National Cancer Institute BMI Pooling Project Various 1.46 (M&F) No
US National Cancer Institute Cohort Consortium Various 9.00 Yes

retrospective and other

Hong Kong Retrospective Study 1997 - 1999 0.04 (M&F) No
Million Death Study 2002 - 2004 14.0* (M&F) No
Indirect Smoking Mortality Estimates 1950 - (M&F) No
INTERHEART retrospective 1999 - 2003 0.03 (M&F) Yes
INTERSTROKE retrospective 2007 - 2014 0.03 (M&F) Yes
NCD Risk Factor Collaboration (NCD-RisC) 1950 - 20 (M&F) No
South Africa Retrospective 1999 -  0.48 (M&F) No

* Planned study size for those studies that have not completed recruitment.

To find out more, to register your study or to amend study details email sarah.lewington@ndph.ox.ac.uk